Ribosome Rescue, Nearing the End

Cell, 2014, DOI: http://dx.doi.org/10.1016/j.cell.2014.02.028, Volume 156, Issue 5, p866–867 published on 27.02.2014
Cell, online article
In eukaryotes, Dom34 is involved in the rescue of ribosomes that stall on mRNAs during protein synthesis. Using ribosome profiling, Guydosh and Green reveal that, in addition to rescue of ribosomes stalled on truncated mRNAs, Dom34 also recycles ribosomes that are unexpectedly found in the 3′ untranslated regions of many cellular mRNAs.

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry