Research Area C - Publications 2019

Cell, 179, 1264–1275, DOI:https://doi.org/10.1016/j.cell.2019.11.001
Cell, online article

carell-hornung-cell_2019_550.100x0.jpg

TLR8 is among the highest-expressed pattern-recognition receptors in the human myeloid compartment, yet its mode of action is poorly understood. TLR8 engages two distinct ligand binding sites to sense RNA degradation products, although it remains unclear how these ligands are formed in cellulo in the context of complex RNA molecule sensing. Here, we identified ...

|READ MORE|

CIPSM Movie
LMUexcellent
TU München
MPG
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry