Peptides in the Ribosomal Tunnel Talk Back
04-Feb-2011
Molecular Cell,, 2011, doi:10.1016/j.molcel.2011.01.017, Volume 41, Issue 3, 247-248, published on 04.02.2011
In this issue of Molecular Cell, Ramu et al. demonstrate that nascent peptides located within the ribosomal tunnel can talk back to the peptidyl transferase center to induce translational stalling by restricting the species of aminoacyl-tRNAs that can bind there.
