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Developmental Cell, Volume 41, Issue 6, p573–574, DOI: http://dx.doi.org/10.1016/j.devcel.2017.06.002
Developmental Cell, online article
Caspases have apoptotic and non-apoptotic functions, both of which depend on their abilities to cleave proteins at specific sites. What distinguishes apoptotic from non-apoptotic substrates has so far been unclear. In this issue of Developmental Cell, Weaver et al. (2017) now provide an answer to this crucial question.