Nick Your DNA, Mark Your Chromatin
Molecular Cell, Volume 64, Issue 1, p7–9, DOI: http://dx.doi.org/10.1016/j.molcel.2016.09.023
Molecular Cell, online article
DNA damage induces chemical and structural changes in our chromatin-embedded genome. In a recent issue of Nature Communications, Grundy et al. (2016) identify a role for PARP3 in the repair of single-strand breaks and reveal that PARP3 mono-ADP-ribosylates nucleosomal histone H2B.