Research Area F - Publications 2021

Chem. Sci., 2021,12, 3743-3750,  DOI: 10.1039/d0sc06060g
Chem. Sci.,, online article

cipsm_huc_sensing_a_binding_event_through_charge_transport_variations_using_an_aromatic_oligoamide_capsule_550.100x0.jpg

The selective binding properties of a 13-mer oligoamide foldamer capsule composed of 4 different aromatic subunits are reported. The capsule was designed to recognize dicarboxylic acids through multiple-point interactions owing to a combination of protonation/deprotonation events, H-bonding, and geometrical constraints imparted by the rigidity of the foldamer ...

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Angew. Chem. Int. Ed. 2021, 60, 8380 –8384, https://doi.org/10.1002/anie.202100349
Angew. Chem. Int. Ed., online article

cipsm_huc_interplay_between_a_foldamer_helix_and_a_macrocycle_in_a_foldarotaxane_architecture_550.100x0.jpg

The design and synthesis of a novel rotaxane/foldaxane hybrid architecture is reported. The winding of an aromatic oligoamide helix host around a dumbbell‐shaped thread‐like guest, or axle, already surrounded by a macrocycle was evidenced by NMR spectroscopy and X‐ray crystallography. The process proved to depend on the position of the macrocycle along the axle ...

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Angew. Chem. Int. Ed. 2021, 60, 2574 –2577, doi.org/10.1002/anie.202014670
Angew. Chem. Int. Ed., online article

huc_large-amplitude_conformational_changes_in_self-assembled_multi-stranded_aromatic_sheets_550.100x0.jpg

The orchestration of ever larger conformational changes is made possible by the development of increasingly complex foldamers. Aromatic sheets, a rare motif in synthetic foldamer structures, have been designed so as to form discrete stacks of intercalated aromatic strands through the self‐assembly of two identical subunits. Ion‐mobility ESI‐MS confirms the ...

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