Stereoselective Total Syntheses of Herbicidin C and Aureonuclemycin through Late-Stage Glycosylation
Angewandte Chemie, 2012, DOI: 10.1002/anie.201201826, Volume 51, Issue 26, pages 6525–6528 published on 29.05.2012
Better late than never! Two herbicidins, members of an important family of nucleoside antibiotics, have been synthesized for the first time. The route integrates a stereoselective C-glycosylation with several reagent-controlled stereoselective transformations and a surprisingly facile and highly diastereoselective late-stage N-glycosylation.