Proteomics reveals a new DNA repair factor involved in DNA damage signaling

Molecular & Cellular Oncology, 4:1, e1263713, DOI:10.1080/23723556.2016.1263713
Molecular & Cellular Oncology, online article

Stalling of the DNA replication machinery activates the ATR checkpoint kinase, which coordinates the cellular responses to replication stress. New studies identify a novel ATR activator, ETAA1, which is indispensable for the maintenance of genome integrity. Dysregulation of ETAA1 may contribute to the development of pancreatic cancer.
 

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