Proteomics reveals a new DNA repair factor involved in DNA damage signaling

Molecular & Cellular Oncology, 4:1, e1263713, DOI:10.1080/23723556.2016.1263713
Molecular & Cellular Oncology, online article

Stalling of the DNA replication machinery activates the ATR checkpoint kinase, which coordinates the cellular responses to replication stress. New studies identify a novel ATR activator, ETAA1, which is indispensable for the maintenance of genome integrity. Dysregulation of ETAA1 may contribute to the development of pancreatic cancer.

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry