Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions

Photochemistry and Photobiology, 2014, DOI: 10.1111/php.12197, Volume 90, Issue 1, pages 1–14, published on 31.01.2014

Photochemistry and Photobiology, online article

Direct repair of UV-induced DNA lesions represents an elegant method for many organisms to deal with these highly mutagenic and cytotoxic compounds. Although the participating proteins are structurally well investigated, the exact repair mechanism of the photolyase enzymes remains a vivid subject of current research. In this review, we summarize and highlight the recent contributions to this exciting field.

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry