Histone glutamine methylation afFACTing rDNA transcription

Cell Research, 2014, doi:10.1038/cr.2014.22, 24:261–262. published on 14.02.2014
Cell Research, online article
Chemical modifications of histone proteins directly and indirectly affect chromatin structure and thereby contribute to the multilayered control of diverse DNA-based processes. A recent study in Nature enriches this list of enzyme-dependent posttranslational histone marks by H2A glutamine methylation that appears to be dedicated to only one specific cellular process, the regulation of nucleolar rDNA transcription.

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry