DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution

Epigenetics & Chromatin, 2014, doi:10.1186/1756-8935-7-17, 2014, 7:17 published on 03.08.2014
Epigenetics & Chromatin, online article
Methyl-CpG binding protein 2 (MECP2) is a protein that specifically binds methylated DNA, thus regulating transcription and chromatin organization. Mutations in the gene have been identified as the principal cause of Rett syndrome, a severe neurological disorder. Although the role of MECP2 has been extensively studied in nervous tissues, still very little is known about its function and cell type specific distribution in other tissues.  

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry