Research Area B - Publications 2017

Molecular Plant, Volume 10, Issue 4, p575–589, http://dx.doi.org/10.1016/j.molp.2016.12.012
Molecular Plant, online article

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The translocon on the outer membrane of mitochondria (TOM) facilitates the import of nuclear-encoded proteins. The principal machinery of mitochondrial protein transport seems conserved in eukaryotes; however, divergence in the composition and structure of TOM components has been observed between mammals, yeast, and plants. TOM9, the plant homolog of yeast Tom22, ...

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JBC, doi: 10.1074/jbc.M117.782284
JBC, online article

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Members of the interleukin 12 (IL12) family perform essential functions in immunoregulation by connecting innate and adaptive immunity and are emerging therapeutic targets. They are unique among other interleukins in forming heterodimers that arise from extensive subunit sharing within the family, leading to the production of at least four functionally distinct ...

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Scientific Reports, 7, Article number: 44277, doi:10.1038/srep44277
Scientific Reports, online article

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Cationic amphiphilic drugs (CADs) comprise a wide variety of different substance classes such as antidepressants, antipsychotics, and antiarrhythmics. It is well recognized that CADs accumulate in certain intracellular compartments leading to specific morphological changes of cells. So far, no adequate technique exists allowing for ultrastructural analysis of CAD ...

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Front. Plant Sci., https://doi.org/10.3389/fpls.2017.00168
Front. Plant Sci., online article

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Chloroplasts originated from an endosymbiotic event in which a free-living cyanobacterium was engulfed by an ancestral eukaryotic host. During evolution the majority of the chloroplast genetic information was transferred to the host cell nucleus. As a consequence, proteins formerly encoded by the chloroplast genome are now translated in the cytosol and must be ...

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