Research Area A - Publications 2020

Nat Commun 11, 4321 (2020). https://doi.org/10.1038/s41467-020-18063-x
Nat.Commun., online article

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Bacterial colonization of the human intestine requires firm adhesion of bacteria to insoluble substrates under hydrodynamic flow. Here we report the molecular mechanism behind an ultrastable protein complex responsible for resisting shear forces and adhering bacteria to cellulose fibers in the human gut. Using single-molecule force spectroscopy (SMFS), ...

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J. Phys. Chem. Lett. 2020, 11, 11, 4462–4480, https://doi.org/10.1021/acs.jpclett.9b03833
J. Phys. Chem. Lett., online article

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Self-healing dyes have emerged as a new promising class of fluorescent labels. They consist of two units, a fluorescent dye and a photostabilizer. The latter heals whenever the fluorescent dye is in danger of taking a reaction pathway toward photobleaching. We describe the underlying concepts and summarize the developmental history and state-of-the-art, including ...

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Nat Commun 11, 2828 (2020),  https://doi.org/10.1038/s41467-020-16702-x
Nat Commun, online article

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The TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor are important constituents of all eukaryotic initiation complexes. The reason for the emergence and strict requirement of the additional initiation factor Bdp1 in the RNA polymerase (RNAP) III system, however, remained elusive. A poorly studied aspect in this context is the effect of ...

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