Research Area A - Publications 2017

ChemBioChem, Volume 18, Issue 13, Pages 1172–1176 , DOI: 10.1002/cbic.201600706
ChemBioChem, online article

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Mycobacterium tuberculosis (Mtb), the main causative agent of tuberculosis (Tb), has a complex cell envelope which forms an efficient barrier to antibiotics, thus contributing to the challenges of anti-tuberculosis therapy. However, the unique Mtb cell wall can be considered an advantage and be utilized to selectively label Mtb bacteria. Here we introduce three ...

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ACS Nano, 11 (2), pp 1498–1508, DOI: 10.1021/acsnano.6b06812
ACS Nano, online article

 

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Advances in the engineering of nanoparticles (NPs), which represent particles of less than 100 nm in one external dimension, led to an increasing utilization of nanomaterials for biomedical purposes. A prerequisite for their use in diagnostic and therapeutic applications, however, is the targeted delivery to the site of injury. Interactions between blood-borne ...

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PLoS ONE 12(1): e0170625, doi:10.1371/journal.pone.0170625
PLOS ONE, online article

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Protein-protein docking protocols aim to predict the structures of protein-protein complexes based on the structure of individual partners. Docking protocols usually include several steps of sampling, clustering, refinement and re-scoring. The scoring step is one of the bottlenecks in the performance of many state-of-the-art protocols. The performance of scoring ...

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